Journal article
Purification of therapeutic adenoviruses using laterally-fed membrane chromatography
Abstract
Viruses are an emerging class of biotherapeutics with the potential to treat cancer, genetic, cardiovascular and other diseases. Their commercial success depends on cost-effective purification processes. Membrane chromatography processes offer great potential for virus purification, however conventional devices are known to suffer from issues related to resolution and sample dilution. Laterally-fed membrane chromatography (LFMC) overcomes these …
Authors
Kawka K; Madadkar P; Umatheva U; Shoaebargh S; Medina MFC; Lichty BD; Ghosh R; Latulippe DR
Journal
Journal of Membrane Science, Vol. 579, , pp. 351–358
Publisher
Elsevier
Publication Date
June 2019
DOI
10.1016/j.memsci.2019.02.056
ISSN
0376-7388