Journal article
Activation of hippocampal microglia in a murine model of cancer-induced pain
Abstract
INTRODUCTION: Pain is a common and debilitating comorbidity of metastatic breast cancer. The hippocampus has been implicated in nociceptive processing, particularly relating to the subjective aspect of pain. Here, a syngeneic mouse model was used to characterize the effects of peripheral tumors on hippocampal microglial activation in relation to cancer-induced pain (CIP).
MATERIALS AND METHODS: Mice were systemically treated with the …
Authors
Miladinovic T; Sharma M; Phan A; Geres H; Ungard RG; Linher-Melville K; Singh G
Journal
Journal of Pain Research, Vol. 12, No. 0, pp. 1003–1016
Publisher
Taylor & Francis
Publication Date
March 18, 2019
DOI
10.2147/jpr.s191860
ISSN
1178-7090