Hb J-Singa (α-78 Asn → Asp), A newly discovered hemoglobin variant with the same amino acid substitution as one of the two present in Hb J-Singapore (α-78 Asn → Asp, α-79 Ala → Gly) Academic Article uri icon

  •  
  • Overview
  •  
  • Research
  •  
  • Identity
  •  
  • Additional Document Info
  •  
  • View All
  •  

abstract

  • A new fast-moving alpha-chain Hb variant with an Asn leads to Asp substitution at position alpha-78 was found in a French-Acadian family living in Eastern Canada. The identical substitution was reported in Hb J-Singapore, which also had an additional Ala leads to Gly substitution at position alpha-79. The new variant, which did not result in any clinical symptoms, was named accordingly, Hb J-Singa.

authors

  • Wong, SC
  • Ali, Mahmoud
  • Pond, JR
  • Rubin, SM
  • Johnson, SEN
  • Wilson, JB
  • Huisman, THJ

publication date

  • January 1984