Hb J-Singa (α-78 Asn → Asp), A newly discovered hemoglobin variant with the same amino acid substitution as one of the two present in Hb J-Singapore (α-78 Asn → Asp, α-79 Ala → Gly)

A new fast-moving alpha-chain Hb variant with an Asn leads to Asp substitution at position alpha-78 was found in a French-Acadian family living in Eastern Canada. The identical substitution was reported in Hb J-Singapore, which also had an additional Ala leads to Gly substitution at position alpha-79. The new variant, which did not result in any clinical symptoms, was named accordingly, Hb J-Singa.