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Fumaric aciduria: a new organic aciduria,...
Journal article

Fumaric aciduria: a new organic aciduria, associated with mental retardation and speech impairment

Abstract

Two siblings are described who present with fumaric aciduria, a hitherto unreported organic aciduria. The results of our analytical investigations using gas chromatography/mass spectrometry, and the clinical presentation of the patients, are consistent with the notion that the fumaric aciduria is caused by an inherited defect which leads to a net secretion of fumaric acid by the renal tubules.

Authors

Whelan DT; Hill RE; McClorry S

Journal

Clinica Chimica Acta, Vol. 132, No. 3, pp. 301–308

Publisher

Elsevier

Publication Date

August 1983

DOI

10.1016/0009-8981(83)90008-6

ISSN

0009-8981