Journal article
Effects of Trypanocidal Treatment on Echocardiographic Parameters in Chagas Cardiomyopathy and Prognostic Value of Wall Motion Score Index: A BENEFIT Trial Echocardiographic Substudy
Abstract
BACKGROUND: Serial echocardiographic studies in chronic Chagas cardiomyopathy are scarce. The aims of this study were to evaluate whether therapy with benznidazole modifies the progression of cardiac impairment and to identify baseline echocardiographic parameters related to prognosis.
METHODS: A prospective substudy was conducted in 1,508 patients with chronic Chagas cardiomyopathy randomized to benznidazole or placebo, who underwent …
Authors
Schmidt A; Romano MMD; Marin-Neto JA; Rao-Melacini P; Rassi A; Mattos A; Avezum Á; Villena E; Sosa-Estani S; Bonilla R
Journal
Journal of the American Society of Echocardiography, Vol. 32, No. 2, pp. 286–295.e3
Publisher
Elsevier
Publication Date
February 2019
DOI
10.1016/j.echo.2018.09.006
ISSN
0894-7317