Journal article
Influence of Surgical Procedures and General Anesthesia on Child Development Before Primary School Entry Among Matched Sibling Pairs.
Abstract
Importance: Substantial preclinical evidence suggests that the developing brain is susceptible to injury from anesthetic drugs. Findings from clinical studies of the neurotoxic effects of anesthesia are mixed, but these effects can be influenced by unmeasured confounding from biological and environmental risk and protective factors on child development.
Objective: To examine the association between surgical procedures that require general …
Authors
O'Leary JD; Janus M; Duku E; Wijeysundera DN; To T; Li P; Maynes JT; Faraoni D; Crawford MW
Journal
JAMA Pediatrics, Vol. 173, No. 1, pp. 29–36
Publisher
American Medical Association (AMA)
Publication Date
January 1, 2019
DOI
10.1001/jamapediatrics.2018.3662
ISSN
2168-6203