Therapeutic equivalence of three metered‐dose inhalers containing salbutamol (Albuterol) in protecting against methacholine‐induced bronchoconstriction in children with asthma

Many pharmaceutical companies sell salbutamol in metered-dose inhalers (MDI) for the treatment of asthma. However, the therapeutic equivalence of the more recently released generic products has not been compared with the original patented product in children. Twenty children with mild to moderate asthma, presently asymptomatic and with normal lung function, were randomly allocated to receive 200 microg of inhaled salbutamol (Albuterol) from …