Journal article
Effects of Isoprostanes and Prostanoids on Porcine Small Intestine
Abstract
The isoprostanes are prostaglandin (PG)-like compounds formed in vivo by free-radical-catalyzed peroxidation of polyunsaturated fatty acids and are synthesized independent of cyclooxygenase. It has been debated whether the biological effects of the isoprostanes are exerted on prostanoid receptors [thromboxane A2 (TP) receptors and prostanoid E (EP) receptors] or on a "unique" isoprostane receptor. We sought to define the receptors involved in …
Authors
Unmack MA; Rangachari PK; Skadhauge E
Journal
Journal of Pharmacology and Experimental Therapeutics, Vol. 296, No. 2, pp. 434–441
Publisher
Elsevier
Publication Date
February 2001
DOI
10.1016/s0022-3565(24)38761-0
ISSN
0022-3565