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Intestinal Effects of Isoprostanes: Evidence for...
Journal article

Intestinal Effects of Isoprostanes: Evidence for the Involvement of Prostanoid EP and TP Receptors 1

Abstract

The isoprostanes, which differ from prostaglandins by the cis orientation of their side chains, are believed to exert their biological effects on either a prostanoid TP receptor or a "unique" isoprostane receptor. Preliminary experiments suggested that canine colonic epithelium possessed no prostanoid TP receptor activity, in contrast to the muscularis mucosae, which responds well to the selective prostanoid TP receptor agonist U46619. To …

Authors

Elmhurst JL; Betti P-A; Rangachari PK

Journal

Journal of Pharmacology and Experimental Therapeutics, Vol. 282, No. 3, pp. 1198–1205

Publisher

Elsevier

Publication Date

September 1997

DOI

10.1016/s0022-3565(24)36950-2

ISSN

0022-3565