Journal article
Recycling the Waste: The Development of a Catalytic Wittig Reaction
Abstract
It's all in the ring: 3‐Methyl‐1‐phenylphospholane‐1‐oxide (4–10 mol %) and an organosilane reducing agent are the key components in the first Wittig reaction catalytic in phosphine. The protocol also functions well on larger scale: a reaction on a 30 mmol scale yielded 3.39 g of product, corresponding to a yield of 67 %.
Authors
O'Brien CJ; Tellez JL; Nixon ZS; Kang LJ; Carter AL; Kunkel SR; Przeworski KC; Chass GA
Journal
Angewandte Chemie International Edition, Vol. 48, No. 37, pp. 6836–6839
Publisher
Wiley
Publication Date
September 2009
DOI
10.1002/anie.200902525
ISSN
1433-7851