Persistently Folded Circular Aromatic Amide Pentamers Containing Modularly Tunable Cation-Binding Cavities with High Ion Selectivity Academic Article uri icon

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abstract

  • In this work, we illustrated a novel design strategy that allows systematically tunable interior properties (effective cavity size, steric crowdedness, and hydrophobicity) contained within a novel class of shape-persistent aromatic pentamers to take place on a scale below 3 A. Such finely tunable structural features are complimented by experimentally observable functional variations in ion-binding potential. Results of the selective, differential binding affinities of three circular pentamers for Li(+), Na(+), K(+), Rb(+), and Cs(+), substantiated by metal-containing crystal structures and computational modeling, are detailed.

authors

  • Qin, Bo
  • Ren, Changliang
  • Ye, Ruijuan
  • Sun, Chang
  • Chiad, Khalid
  • Chen, Xiuying
  • Li, Zhao
  • Xue, Feng
  • Su, Haibin
  • Chass, Gregory
  • Zeng, Huaqiang

publication date

  • July 21, 2010