Journal article
Effect of Antidepressants and Psychological Therapies in Irritable Bowel Syndrome: An Updated Systematic Review and Meta-analysis
Abstract
ObjectivesIrritable bowel syndrome (IBS) is a chronic functional bowel disorder that is thought to be due to a disorder of brain–gut function. Drugs acting centrally, such as antidepressants, and psychological therapies may, therefore, be effective.MethodsWe updated a previous systematic review and meta-analysis of randomized controlled trials (RCTs). MEDLINE, EMBASE, PsychINFO, and the Cochrane Controlled Trials Register were searched (up to …
Authors
Ford AC; Lacy BE; Harris LA; Quigley EM; Moayyedi P
Journal
The American Journal of Gastroenterology, Vol. 114, No. 1, pp. 1–16
Publisher
Wolters Kluwer
Publication Date
January 2019
DOI
10.1038/s41395-018-0222-5
ISSN
0002-9270