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Serial Susceptibility Weighted MRI Measures Brain...
Journal article

Serial Susceptibility Weighted MRI Measures Brain Iron and Microbleeds in Dementia

Abstract

A new iron sensitive MR sequence (susceptibility weighted imaging - SWI) enabling the simultaneous quantitation of regional brain iron levels and brain microbleeds (BMB) has been acquired serially to study dementia. Cohorts of mildly cognitively impaired (MCI) elderly (n = 73) and cognitively normal participants (n = 33) have been serially evaluated for up to 50 months. SWI phase values (putative iron levels) in 14 brain regions were measured …

Authors

Kirsch W; McAuley G; Holshouser B; Petersen F; Ayaz M; Vinters HV; Dickson C; Haacke EM; Britt W; Larsen J

Journal

Journal of Alzheimer’s Disease, Vol. 17, No. 3, pp. 599–609

Publisher

SAGE Publications

Publication Date

2009

DOI

10.3233/jad-2009-1073

ISSN

1387-2877