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Intestinal permeability in allergic rats: nerve...

Journal article

Intestinal permeability in allergic rats: nerve involvement in antigen-induced changes

Abstract

In vivo uptake of the probe 51Cr-labeled EDTA from the jejunum of egg albumin (EA)-sensitized rats was compared with controls at baseline and after intraluminal antigen challenge. Probe recovery in blood was 60-80% greater in sensitized animals during the baseline period, suggesting that sensitization resulted in increased intestinal permeability. Sensitized, but not control, rats demonstrated a 15-fold increase in 51Cr-EDTA uptake after …

Authors

Crowe SE; Soda K; Stanisz AM; Perdue MH

Journal

American Journal of Physiology-Gastrointestinal and Liver Physiology, Vol. 264, No. 4, pp. G617–G623

Publisher

American Physiological Society

Publication Date

April 1, 1993

DOI

10.1152/ajpgi.1993.264.4.g617

ISSN

0193-1857

Associated Experts

Mary Perdue

Professor Emeritus, Faculty of Health Sciences

Labels

Medical Subject Headings (MeSH)

Anaphylaxis Animals Cell Membrane Permeability Electric Conductivity Electrophysiology Epithelium Hypersensitivity Immunoglobulin E Jejunum Male Membrane Potentials Muscle, Smooth Ovalbumin Rats Rats, Sprague-Dawley Tetrodotoxin

Fields of Research (FoR)

3202 Clinical sciences 3208 Medical physiology

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