Molecular Evolution of Respiratory Syncytial Virus Fusion Gene, Canada, 2006–2010 Academic Article uri icon

  •  
  • Overview
  •  
  • Research
  •  
  • Identity
  •  
  • Additional Document Info
  •  
  • View All
  •  

abstract

  • To assess molecular evolution of the respiratory syncytial virus (RSV) fusion gene, we analyzed RSV-positive specimens from 123 children in Canada who did or did not receive RSV immunoprophylaxis (palivizumab) during 2006-2010. Resistance-conferring mutations within the palivizumab binding site occurred in 8.7% of palivizumab recipients and none of the nonrecipients.

authors

  • Papenburg, Jesse
  • Carbonneau, Julie
  • Hamelin, Marie-Ève
  • Isabel, Sandra
  • Bouhy, Xavier
  • Ohoumanne, Najwa
  • Déry, Pierre
  • Paes, Bosco
  • Corbeil, Jacques
  • Bergeron, Michel G
  • De Serres, Gaston
  • Boivin, Guy

publication date

  • January 2012