Journal article
Calpain activity in bone marrow transplant-associated thrombotic thrombocytopenic purpura
Abstract
The pathophysiology of thrombotic thrombocytopenic purpura (TTP) is not well understood. Recent studies have described a platelet aggregating factor which has been characterized as a calcium-dependent cysteine protease (calpain) in patients with TTP. A type of TTP, sometimes called secondary TTP, has been associated with bone marrow transplantation (BMT). However, unlike primary adult TTP, BMT-TTP has important differences and often does not …
Authors
Zeigler Z; Kelton J; Moore J; Shadduck R; III D; Nath R; Agha M
Journal
Bone Marrow Transplantation, Vol. 24, No. 6, pp. 641–645
Publisher
Springer Nature
Publication Date
September 1, 1999
DOI
10.1038/sj.bmt.1701928
ISSN
0268-3369