Quantitation of red cell membrane associated immunoglobulin in children with Plasmodium falciparum parasitaemia

Erythrocyte-associated IgG was measured on washed red cells from 26 children with P. falciparum parasitaemia using an immunoradiometric assay. The values obtained were compared with 15 age-matched controls living in the same area who did not have malaria. The amount of red cell-associated IgG was related to the haemoglobin concentration, degree of parasitaemia and serum immunoglobulin level. The mean red cell-associated immunoglobulin for …