Journal article
Regulation of Ornithine Aminotransferase in Retinoblastomas*
Abstract
Ornithine-delta-aminotransferase (OAT) is a nuclear-encoded, mitochondrial enzyme that converts ornithine to glutamate semialdehyde. Although OAT is expressed in most tissues of the rat, liver, kidney, and retina have the highest levels of OAT activity. Studies of OAT regulation in liver and kidney have indicated transcriptional and translational controls for the enzyme in a tissue-specific manner. Little is known about OAT modulation in …
Authors
Fagan RJ; Sheffield WP; Rozen R
Journal
Journal of Biological Chemistry, Vol. 264, No. 34, pp. 20513–20517
Publisher
Elsevier
Publication Date
December 1989
DOI
10.1016/s0021-9258(19)47092-0
ISSN
0021-9258