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Docetaxel Plus Prednisone or Mitoxantrone Plus...
Journal article

Docetaxel Plus Prednisone or Mitoxantrone Plus Prednisone for Advanced Prostate Cancer: Updated Survival in the TAX 327 Study

Abstract

PURPOSE: The TAX 327 study compared docetaxel administered every 3 weeks (D3), weekly docetaxel (D1), and mitoxantrone (M), each with prednisone (P), in 1,006 men with metastatic hormone-resistant prostate cancer (HRPC). The original analysis, undertaken in August 2003 when 557 deaths had occurred, showed significantly better survival and response rates for pain, prostate-specific antigen (PSA), and quality of life for D3P when compared with …

Authors

Berthold DR; Pond GR; Soban F; de Wit R; Eisenberger M; Tannock IF

Journal

Journal of Clinical Oncology, Vol. 26, No. 2, pp. 242–245

Publisher

American Society of Clinical Oncology (ASCO)

Publication Date

January 10, 2008

DOI

10.1200/jco.2007.12.4008

ISSN

0732-183X