Journal article
Challenges in defining type 2M von Willebrand disease: results from a Canadian cohort study
Abstract
BACKGROUND/METHODS: In order to better characterize the genotype-phenotype correlation in type 2M von Willebrand disease (VWD), we sequenced the coding region for the mature subunit of the von Willebrand factor (VWF) gene (exons 18-52, including exon/intron boundaries) in 16 index cases originally submitted to the Canadian Type 1 VWD Study as type 1 VWD, but reclassified as type 2M VWD on the basis of phenotype (excessive mucocutaneous bleeding …
Authors
JAMES PD; NOTLEY C; HEGADORN C; POON M; WALKER I; RAPSON D; DIRECTORS OF CANADA AOHC; LILLICRAP D
Journal
Journal of Thrombosis and Haemostasis, Vol. 5, No. 9, pp. 1914–1922
Publisher
Elsevier
Publication Date
September 2007
DOI
10.1111/j.1538-7836.2007.02666.x
ISSN
1538-7933