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NMDA receptor-mediated modulation of dopamine...
Conference

NMDA receptor-mediated modulation of dopamine neuro-transmission in the central nervous system

Abstract

A deficiency in glutamateigic neurotransmission resulting in a disturbed balance between glutamatergic and dopaminergic systems in CNS has been implicated in pathophysiology of schizophrenia. In order to investigate the interaction between N-methyl D-aspartate (NMDA) and dopamine (DA) receptors in the CNS, we examined the effect of an NMDA receptor antagonist, 3(2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP) on DA neurotransmission. …

Authors

Nair VD; Savelli JE; Mishra RK

Volume

10

Publication Date

December 1, 1996

Conference proceedings

FASEB Journal

Issue

3

ISSN

0892-6638