Quantitative biology of single neurons Journal Articles

abstract

• The building blocks of complex biological systems are single cells. Fundamental insights gained from single-cell analysis promise to provide the framework for understanding normal biological systems development as well as the limits on systems/cellular ability to respond to disease. The interplay of cells to create functional systems is not well understood. Until recently, the study of single cells has concentrated primarily on morphological and physiological characterization. With the application of new highly sensitive molecular and genomic technologies, the quantitative biochemistry of single cells is now accessible.

authors

• Eberwine, James
• Lovatt, Ditte
• Buckley, Peter
• Dueck, Hannah
• Francis, Chantal
• Kim, Tae Kyung
• Lee, John
• Lee, Miler
• Miyashiro, Kevin
• Morris, Jacqueline
• Peritz, Tiina
• Schochet, Terri
• Spaethling, Jennifer
• Sul, Jai-Yoon
• Kim, Junhyong

status

• published 

publication date

• December 7, 2012

has subject area

• Electrophysiology (MeSH)
• Gene Expression Regulation (MeSH)
• General Science & Technology (Science Metrix)
• In Situ Hybridization (MeSH)
• Ion Channels (MeSH)
• Neurons (MeSH)
• Protein Biosynthesis (MeSH)
• Proteomics (MeSH)
• Single-Cell Analysis (MeSH)
• Stochastic Processes (MeSH)
• Transcriptome (MeSH)

published in

• Journal of the Royal Society Interface  Journal

keywords

• Electrophysiology
• Gene Expression Regulation
• In Situ Hybridization
• Ion Channels
• Neurons
• Protein Biosynthesis
• Proteomics
• Single-Cell Analysis
• Stochastic Processes
• Transcriptome

Digital Object Identifier (DOI)

• 10.1098/rsif.2012.0417

start page

• 3165

end page

• 3183

volume

• 9

issue

• 77