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Association of intracortical myelin and cognitive...
Journal article

Association of intracortical myelin and cognitive function in bipolar I disorder

Abstract

OBJECTIVE: Although cognitive dysfunction persists through affective and euthymic states in bipolar disorder (BD), its neurobiological correlates remain undetermined. We explore whole-cortex intracortical myelin (ICM) and cognition in BD-I and controls. METHODS: T1 -weighted images (3T) optimized for ICM measurement were analyzed using a surface-based approach. MRI signal was sampled at cortical mid-depth. Cognitive performance was measured via …

Authors

Sehmbi M; Rowley CD; Minuzzi L; Kapczinski F; Steiner M; Sassi RB; Bock NA; Frey BN

Journal

Acta Psychiatrica Scandinavica, Vol. 138, No. 1, pp. 62–72

Publisher

Wiley

Publication Date

July 2018

DOI

10.1111/acps.12875

ISSN

0001-690X