Conference
Abstract 3233: Targeting system xc- in breast cancer cells: Development of novel therapeutics
Abstract
Abstract
Cancer-induced bone pain is a major palliative condition suffered by many afflicted with breast cancer. With current anti-cancer therapeutics prolonging the lives of these patients without eradicating the disease itself, quality of life concerns predominate patient care. A potential mechanism implicates glutamate, and specifically the glutamate-cystine antiporter called system xc-. Due to the accelerated metabolism of …
Authors
Fazzari J; Lin H; Linher-Melville K; Singh G
Volume
74
Pagination
pp. 3233-3233
Publisher
American Association for Cancer Research (AACR)
Publication Date
October 1, 2014
DOI
10.1158/1538-7445.am2014-3233
Conference proceedings
Cancer Research
Issue
19_Supplement
ISSN
0008-5472