Journal article
Maternal depressive symptoms linked to reduced fecal Immunoglobulin A concentrations in infants
Abstract
Secretory Immunoglobulin A (sIgA) plays a critical role to infant gut mucosal immunity. Delayed IgA production is associated with greater risk of allergic disease. Murine models of stressful events during pregnancy and infancy show alterations in gut immunity and microbial composition in offspring, but little is known about the stress-microbiome-immunity pathways in humans. We investigated differences in infant fecal sIgA concentrations …
Authors
Kang LJ; Koleva PT; Field CJ; Giesbrecht GF; Wine E; Becker AB; Mandhane PJ; Turvey SE; Subbarao P; Sears MR
Journal
Brain Behavior and Immunity, Vol. 68, , pp. 123–131
Publisher
Elsevier
Publication Date
February 2018
DOI
10.1016/j.bbi.2017.10.007
ISSN
0889-1591