Journal article
The minimal detectable change cannot reliably replace the minimal important difference
Abstract
OBJECTIVE: We compared the minimal important difference (MID) with the minimal detectable change (MDC) generated by distribution-based methods.
STUDY DESIGN: Studies of two quality-of-life instruments (Chronic Respiratory Questionnaire [CRQ] and Rhinoconjunctivitis Quality of Life Questionnaire [RQLQ]) and two physician-rated disease-activity indices (Pediatric Ulcerative Colitis Activity Index [PUCAI] and Pediatric Crohn's Disease Activity …
Authors
Turner D; Schünemann HJ; Griffith LE; Beaton DE; Griffiths AM; Critch JN; Guyatt GH
Journal
Journal of Clinical Epidemiology, Vol. 63, No. 1, pp. 28–36
Publisher
Elsevier
Publication Date
January 2010
DOI
10.1016/j.jclinepi.2009.01.024
ISSN
0895-4356