Journal article
Changes in inhibitory processes in the hippocampus following recurrent seizures induced by systemic administration of kainic acid
Abstract
Rats were chronically prepared with stimulation electrodes in the angular bundle and recording electrodes in the dentate gyrus under electrophysiological guidance. Following testing of dentate gyrus field potentials, the animals were given a single injection of kainic acid which caused repeated seizures and led to status epilepticus. The seizures were stopped by administration of a barbiturate anesthetic after 60 min. Changes in inhibition …
Authors
Milgram NW; Yearwood T; Khurgel M; Ivy GO; Racine R
Journal
Brain Research, Vol. 551, No. 1-2, pp. 236–246
Publisher
Elsevier
Publication Date
6 1991
DOI
10.1016/0006-8993(91)90938-r
ISSN
0006-8993