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A role for corticotropin releasing factor (CRF) in...
Journal article

A role for corticotropin releasing factor (CRF) in ethanol consumption, sensitivity, and reward as revealed by CRF-deficient mice

Abstract

Rationale. Corticotropin-releasing factor (CRF) plays an integral role in mediating stress responses and anxiety. However, little is known regarding the role of CRF in ethanol consumption, a behavior often associated with stress and anxiety in humans.Objective. The present study sought to determine the role of CRF in ethanol consumption, locomotor sensitivity and reward by examining these behaviors in C57BL/6J × 129S mice with a targeted …

Authors

Olive FM; Mehmert KK; Koenig HN; Camarini R; Kim JA; Nannini MA; Ou CJ; Hodge CW

Journal

Psychopharmacology, Vol. 165, No. 2, pp. 181–187

Publisher

Springer Nature

Publication Date

January 2003

DOI

10.1007/s00213-002-1248-2

ISSN

0033-3158