Journal article
A New Twist in the Assembly of Type IV Pilus-like Fibers
Abstract
The type II secretion system (T2SS) and the type IV pilus system (T4PS) are structurally related molecular machines that reversibly assemble helical fibers in an ATP-dependent manner. In this issue of Structure, Nivaskumar and colleagues provide support for a "spooling" model of T2SS pseudopilus assembly and suggest that the T2S-and by extension, T4P-system motors may operate in a rotary manner to assemble filaments.
Authors
Burrows LL
Journal
Structure, Vol. 22, No. 5, pp. 659–661
Publisher
Elsevier
Publication Date
May 2014
DOI
10.1016/j.str.2014.04.009
ISSN
0969-2126