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Effects of Estrogens on Adipokines and Glucose...
Journal article

Effects of Estrogens on Adipokines and Glucose Homeostasis in Female Aromatase Knockout Mice

Abstract

The maintenance of glucose homeostasis within the body is crucial for constant and precise performance of energy balance and is sustained by a number of peripheral organs. Estrogens are known to play a role in the maintenance of glucose homeostasis. Aromatase knockout (ArKO) mice are estrogen-deficient and display symptoms of dysregulated glucose metabolism. We aim to investigate the effects of estrogen ablation and exogenous estrogen …

Authors

Van Sinderen ML; Steinberg GR; Jørgensen SB; Honeyman J; Chow JD; Herridge KA; Winship AL; Dimitriadis E; Jones MEE; Simpson ER

Journal

PLOS ONE, Vol. 10, No. 8,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0136143

ISSN

1932-6203