Conference
439 MULTIPLE HORMONE RESISTANCE IN PSEUDOHYPOPARATHYROIDISM TYPE(PHP-1)
Abstract
PHP-1 can be divided into 2 groups, with either diminished(A)or normal (B) G stimulatory regulatory protein activity(Gs) of the hormone receptor-adenylate cyclase system. In 14 PHP-1 patients (pts), aged 9 mos to 22 yrs we measured erythrocyte Gs protein activity and performed detailed endocrine evaluation for evidence of multiple hormonal dysfunction, as previously shown in PHP-1A adults (Am J Med 1983:74,545).Results: 6 pts had PHP-1A (↓Gs) …
Authors
Costigan DC; Holland FJ; Levine MA; Kooh SW; Eraser D
Volume
19
Pagination
pp. 184-184
Publisher
Springer Nature
Publication Date
April 1985
DOI
10.1203/00006450-198504000-00469
Conference proceedings
Pediatric Research
Issue
4
ISSN
0031-3998