Journal article
Influence of filler selection on twin screw foam granulation
Abstract
The influence of filler selection in wet granulation was studied for the novel case where the binder is delivered as an unstable, semi-rigid aqueous foam to an extrusion process. The work primarily examined the impact of differing concentrations of microcrystalline cellulose (Avicel PH® 101) in a formulation with spray-dried α-lactose monohydrate (Flowlac® 100) in regards to wetting and granule nucleation for this relatively new technique known …
Authors
Rocca KE; Weatherley S; Sheskey PJ; Thompson MR
Journal
Drug Development and Industrial Pharmacy, Vol. 41, No. 1, pp. 35–42
Publisher
Taylor & Francis
Publication Date
January 2, 2015
DOI
10.3109/03639045.2013.845839
ISSN
0363-9045