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Adjunctive vitamin D for treatment of active...
Journal article

Adjunctive vitamin D for treatment of active tuberculosis in India: a randomised, double-blind, placebo-controlled trial

Abstract

BACKGROUND: Vitamin D has immunomodulatory effects that might aid clearance of mycobacterial infection. We aimed to assess whether vitamin D supplementation would reduce time to sputum culture conversion in patients with active tuberculosis. METHODS: We did this randomised, double-blind, placebo-controlled, superiority trial at 13 sites in India. Treatment-naive patients who were sputum-smear positive, HIV negative, and had pulmonary …

Authors

Daley P; Jagannathan V; John KR; Sarojini J; Latha A; Vieth R; Suzana S; Jeyaseelan L; Christopher DJ; Smieja M

Journal

The Lancet Infectious Diseases, Vol. 15, No. 5, pp. 528–534

Publisher

Elsevier

Publication Date

May 2015

DOI

10.1016/s1473-3099(15)70053-8

ISSN

1473-3099