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Assignment of multiple endocrine neoplasia type 2A...
Journal article

Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage

Abstract

Abstract Multiple endocrine neoplasis type 2A (MEN2A) is one of several kinds of cancers that appear to be inherited in an autosomally dominant fashion. We have assigned the MEN2A locus to chromosome 10 by linkage with a new DNA marker (D10S5). The linkage led us to investigate other chromosome 10 markers and demonstrate linkage between the disease locus and the interstitial retinol-binding protein (IRBP) gene1. The D10S5 locus was sublocalized …

Authors

Simpson NE; Kidd KK; Goodfellow PJ; McDermid H; Myers S; Kidd JR; Jackson CE; Duncan AMV; Farrer LA; Brasch K

Journal

Nature, Vol. 328, No. 6130, pp. 528–530

Publisher

Springer Nature

Publication Date

August 1987

DOI

10.1038/328528a0

ISSN

0028-0836