Journal article
A DNA marker closely linked to the factor IX (haemophilia B) gene
Abstract
We have isolated a DNA segment, pX58dIIIc, from an X-chromosome library which identifies an SstI restriction fragment length polymorphism (RFLP) at locus DXS99. Linkage analysis in six informative families has shown that the DXS99 locus lies close to the factor IX gene (F9). No recombination was detected between these loci in 39 informative meioses (Z=9.79, θ=0.0). Therefore, DXS99 will be useful as a DNA marker for the assessment of carrier …
Authors
Mulligan L; Holden JJA; White BN
Journal
Human Genetics, Vol. 75, No. 4, pp. 381–383
Publisher
Springer Nature
Publication Date
4 1987
DOI
10.1007/bf00284113
ISSN
0340-6717