Journal article
Preparation of Monodisperse Biodegradable Polymer Microparticles Using a Microfluidic Flow‐Focusing Device for Controlled Drug Delivery
Abstract
Degradable microparticles have broad utility as vehicles for drug delivery and form the basis of several therapies approved by the US Food and Drug Administration. Conventional emulsion-based methods of manufacturing produce particles with a wide range of diameters (and thus kinetics of release) in each batch. This paper describes the fabrication of monodisperse, drug-loaded microparticles from biodegradable polymers using the microfluidic …
Authors
Xu Q; Hashimoto M; Dang TT; Hoare T; Kohane DS; Whitesides GM; Langer R; Anderson DG
Journal
Small, Vol. 5, No. 13, pp. 1575–1581
Publisher
Wiley
Publication Date
July 3, 2009
DOI
10.1002/smll.200801855
ISSN
1613-6810