Journal article
Diagnostic and prognostic validity of the human papillomavirus E6/E7 mRNA test in cervical cytological samples of HC2-positive patients
Abstract
The study aimed to assess the clinical utility in identifying CIN2 or worse (CIN2+), of the Pretect HPV-Proofer test for E6/E7 mRNA detection in Hybrid Capture 2 (HC2)-positive patients, who underwent colposcopy. In particular, the study analyzed the mRNA test performance as the third test in a subgroup of HC2+ patients with less severe than high-grade squamous intraepithelial lesions (HSIL−). We analyzed 464 cervico-vaginal samples by …
Authors
Benevolo M; Terrenato I; Mottolese M; Marandino F; Carosi M; Rollo F; Ronchetti L; Muti P; Mariani L; Sindico S
Journal
Cancer Causes & Control, Vol. 22, No. 6, pp. 869–875
Publisher
Springer Nature
Publication Date
June 2011
DOI
10.1007/s10552-011-9757-0
ISSN
0957-5243
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdolescentAdultAgedCervix UteriCytodiagnosisDiagnostic Techniques, Obstetrical and GynecologicalFemaleHumansMiddle AgedOncogene Proteins, ViralPapillomavirus E7 ProteinsPapillomavirus InfectionsPredictive Value of TestsPrognosisRNA, MessengerRNA, ViralRepressor ProteinsUterine Cervical NeoplasmsYoung AdultUterine Cervical Dysplasia