Journal article
Single Nucleotide Polymorphisms Alter the Promoter Activity of Bovine MIF
Abstract
Macrophage migration inhibitory factor (MIF) is a unique pro-inflammatory cytokine whose chief functions include modulating TLR4 expression, and suppressing the anti-inflammatory effects of glucocorticoids. Not surprisingly, MIF is involved in a number of inflammatory diseases and single nucleotide polymorphisms (SNPs) have been implicated in modulating disease severity. The objective of the present study was to determine if SNPs in 5' region …
Authors
Verschoor CP; Pant SD; You Q; Schenkel FS; Kelton DF; Karrow NA
Journal
Animal Biotechnology, Vol. 22, No. 3, pp. 143–150
Publisher
Taylor & Francis
Publication Date
July 2011
DOI
10.1080/10495398.2011.580219
ISSN
1049-5398