Journal article
CYB5D2 enhances HeLa cells survival of etoposide-induced cytotoxicity
Abstract
Cytochrome b5 domain containing 2 (CYB5D2) (neuferricin) belongs to the family of membrane-associated progesterone receptors (MAPRs). MAPRs affect multiple cellular processes, including proliferation, differentiation, and survival. Consistent with these observations, we report here that CYB5D2 enhances HeLa cells survival of etoposide (ETOP)-mediated cytotoxicity. Overexpression of CYB5D2 enhanced the survival of HeLa cells compared with HeLa …
Authors
Xie Y; Bruce A; He L; Wei F; Tao L; Tang D
Journal
Biochemistry and Cell Biology, Vol. 89, No. 3, pp. 341–350
Publisher
Canadian Science Publishing
Publication Date
June 2011
DOI
10.1139/o11-004
ISSN
0829-8211
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Amino Acid SequenceApoptosisBlotting, WesternCell SurvivalCytochromes b5EtoposideFlow CytometryFluorescent Antibody TechniqueGene ExpressionGene Expression ProfilingHeLa CellsHumansMolecular Sequence DataOrgan SpecificityPlasmidsProtein Structure, TertiaryRecombinant ProteinsTransfectionTumor Necrosis Factor-alphaUltraviolet Rays