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Hemoglobin H identification by high‐performance...
Journal article

Hemoglobin H identification by high‐performance liquid chromatography in confirmed hemoglobin H disease

Abstract

INTRODUCTION: Among hemoglobin (Hb) H disease cases diagnosed by DNA testing in our hemoglobinopathy laboratory, we have noted instances of unreported Hb H from high-performance liquid chromatography (HPLC) results of referring laboratories. METHODS: To characterize these issues, we identified all cases of genotypic Hb H disease diagnosed in our laboratory. HPLC chromatograms were reviewed to determine the presence and retention time of the Hb …

Authors

Turley E; McFarlane A; Halchuk L; Verhovsek M

Journal

International Journal of Laboratory Hematology, Vol. 37, No. 5, pp. 668–672

Publisher

Wiley

Publication Date

10 2015

DOI

10.1111/ijlh.12382

ISSN

1751-5521