Journal article
Effect of long-term ACE-inhibitor therapy in elderly vascular disease patients
Abstract
AIMS: Cardiovascular (CV) disease is the leading cause of death in the elderly. The use of ACE-inhibitors in elderly patients with chronic stable vascular disease has not been previously reported.
METHODS AND RESULTS: The HOPE trial evaluated the effects of ramipril and vitamin E in high-risk vascular disease patients. We report the effects of ramipril in the elderly HOPE study patients, defined as those > or =70 years of age. A total of 2755 …
Authors
Gianni M; Bosch J; Pogue J; Probstfield J; Dagenais G; Yusuf S; Lonn E
Journal
European Heart Journal, Vol. 28, No. 11, pp. 1382–1388
Publisher
Oxford University Press (OUP)
Publication Date
June 1, 2007
DOI
10.1093/eurheartj/ehm017
ISSN
0195-668X