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A randomized trial of maintenance versus no...
Journal article

A randomized trial of maintenance versus no maintenance melphalan and prednisone in responding multiple myeloma patients

Abstract

In order to assess the role of maintenance melphalan and prednisone (MP) in responding multiple myeloma patients, 185 eligible patients who responded to initial MP with stabilization for at least 4 months were randomized to either stop treatment and resume therapy at relapse or to continue MP until relapse. Time to first relapse was significantly shorter in the no maintenance group (P = 0.0011), however 57% of the no maintenance patients had a …

Authors

Belch A; Shelley W; Bergsagel D; Wilson K; Klimo P; White D; Willan A

Journal

British Journal of Cancer, Vol. 57, No. 1, pp. 94–99

Publisher

Springer Nature

Publication Date

January 1988

DOI

10.1038/bjc.1988.17

ISSN

0007-0920