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Why different trials on digitalis give conflicting...
Journal article

Why different trials on digitalis give conflicting data

Abstract

Taking a careful look at each of the outcomes measured in randomized, controlied trials of digoxin suggest that discrepancies in results may be more apparent than real. Digoxin does work, but clinically important benefit is restricted to a relatively small proportion of congestive heart failure (CHF) patients. The play of chance, the dose of digozin used, and the severity of heart failure in patients enrolled in the studies are other factors …

Authors

Jaeschke R; Guyatt GH

Journal

Cardiovascular Drugs and Therapy, Vol. 2, No. 6, pp. 727–731

Publisher

Springer Nature

Publication Date

January 1989

DOI

10.1007/bf00133200

ISSN

0920-3206