Journal article
Coagulopathy related to dilution and hypotension during massive transfusion
Abstract
A retrospective review of 64 patients receiving more than 10 units of red cell concentrate plus crystalloid within 12 h revealed two consecutive patterns of elevation of the partial thromboplastin time (PTT). The PTT at 3 to 4 h (PTT3-4) correlated with the number of liters of crystalloid (LC) infused over the first 3 h (PTT3-4 = 37 + 7 LC, r = .7643, p less than .001); the PTT thereafter (PTT4+) correlated with the number of hours of closely …
Authors
HEWSON JR; NEAME PB; KUMAR N; AYRTON A; GREGOR P; DAVIS C; SHRAGGE BW
Journal
Critical Care Medicine, Vol. 13, No. 5, pp. 387–391
Publisher
Wolters Kluwer
Publication Date
May 1985
DOI
10.1097/00003246-198505000-00003
ISSN
0090-3493