Calcium antagonists and acute renal failure

PURPOSE: To critically review the question of whether calcium antagonists can prevent or attenuate post-ischemic acute renal failure (ARF). PATIENTS AND METHODS: Using a computer-assisted search, we identified all experimental and clinical studies published in English between 1980 and 1988 in which the main research question addressed the efficacy of verapamil, diltiazem, or nifedipine in the treatment of post-ischemic ARF. Studies were then …