Journal article
Effects of centrally acting ACE inhibitors on the rate of cognitive decline in dementia
Abstract
OBJECTIVES: There is growing evidence that antihypertensive agents, particularly centrally acting ACE inhibitors (CACE-Is), which cross the blood-brain barrier, are associated with a reduced rate of cognitive decline. Given this, we compared the rates of cognitive decline in clinic patients with dementia receiving CACE-Is (CACE-I) with those not currently treated with CACE-Is (NoCACE-I), and with those who started CACE-Is, during their first 6 …
Authors
Gao Y; O'Caoimh R; Healy L; Kerins DM; Eustace J; Guyatt G; Sammon D; Molloy DW
Journal
BMJ Open, Vol. 3, No. 7,
Publisher
BMJ
Publication Date
July 2013
DOI
10.1136/bmjopen-2013-002881
ISSN
2044-6055