Journal article
Defining Breast Cancer Intrinsic Subtypes by Quantitative Receptor Expression
Abstract
PURPOSE: To determine intrinsic breast cancer subtypes represented within categories defined by quantitative hormone receptor (HR) and HER2 expression.
METHODS: We merged 1,557 cases from three randomized phase III trials into a single data set. These breast tumors were centrally reviewed in each trial for quantitative ER, PR, and HER2 expression by immunohistochemistry (IHC) stain and by reverse transcription-quantitative polymerase chain …
Authors
Cheang MCU; Martin M; Nielsen TO; Prat A; Voduc D; Rodriguez‐Lescure A; Ruiz A; Chia S; Shepherd L; Ruiz‐Borrego M
Journal
The Oncologist, Vol. 20, No. 5, pp. 474–482
Publisher
Oxford University Press (OUP)
Publication Date
May 1, 2015
DOI
10.1634/theoncologist.2014-0372
ISSN
1083-7159