Journal article
Cigarette smoke aggravates experimental colitis in rats
Abstract
BACKGROUND & AIMS: Tobacco smoking has a complex effect on intestinal inflammation, being protective in ulcerative colitis, whereas it aggravates Crohn's disease. The beneficial effect of smoking has been attributed to nicotine, but the mechanisms underlying the adverse effect are still under investigation. The aim of this study was to examine the effect of cigarette smoking on experimental colitis in rats and to investigate the underlying …
Authors
Galeazzi F; Blennerhassett PA; Qiu B; O'byrne PM; Collins SM
Journal
Gastroenterology, Vol. 117, No. 4, pp. 877–883
Publisher
Elsevier
Publication Date
October 1999
DOI
10.1016/s0016-5085(99)70346-x
ISSN
0016-5085