Journal article
Intestinal inflammation and activation of sensory nerve pathways: a functional and morphological study in the nematode infected rat
Abstract
BACKGROUND: In the rat, gastric distension elicits an intensity dependent pseudoaffective bradycardia mediated via capsaicin sensitive afferent and cholinergic efferent vagal pathways. Inflammation alters visceral perception although the mediators responsible have not been identified. In the nematode infected rat, there is a substantial increase in neuronal substance P (SP) content of the gut.
AIMS: To examine the effects of inflammation on …
Authors
De Giorgio R; Barbara G; Blennerhassett P; Wang L; Stanghellini V; Corinaldesi R; Collins SM; Tougas G
Journal
Gut, Vol. 49, No. 6,
Publisher
BMJ
Publication Date
December 1, 2001
DOI
10.1136/gut.49.6.822
ISSN
0017-5749