Journal article
The protective effect of the vagus nerve in a murine model of chronic relapsing colitis
Abstract
The vagus nerve inhibits the response to systemic administration of endotoxin, and we have recently extended this observation to show that the vagus attenuates acute experimental colitis in mice. The purpose of the present study was to determine whether there is a tonic counterinflammatory influence of the vagus on colitis maintained over several weeks. We assessed disease activity index, macroscopic and histological damage, myeloperoxidase …
Authors
Ghia J-E; Blennerhassett P; El-Sharkawy RT; Collins SM
Journal
AJP Gastrointestinal and Liver Physiology, Vol. 293, No. 4, pp. g711–g718
Publisher
American Physiological Society
Publication Date
October 2007
DOI
10.1152/ajpgi.00240.2007
ISSN
0193-1857